Scientist II Antibody Purification & Conjugation, Second Shift

Scientist II Antibody Purification & Conjugation (2nd Shift) Location: Carlsbad, CA (Onsite)Schedule: Monday-Friday | 1:00 PM-9:30 PM Make an Impact in Life Science Research Join a growing team focused on developing high-quality reagents that support cutting-edge cell signaling and biomedical research worldwide. We are seeking a motivated Scientist II to support antibody purification and bioconjugation manufacturing operations on our second-shift team.In this hands-on laboratory role, you will utilize advanced chromatography techniques, purification platforms, and analytical methods to produce monoclonal antibodies and fluorescently labeled bioconjugates used by researchers around the globe. This is an excellent opportunity for scientists with experience in protein purification, antibody production, FPLC, ÄKTA systems, or biotechnology manufacturing who are looking to expand their technical expertise and take ownership of critical production processes.

Key Responsibilities

• Purify monoclonal antibodies from hybridoma cell cultures using affinity chromatography and related protein purification techniques.
• Operate and maintain chromatography systems, including ÄKTA and FPLC platforms.
• Execute multiple purification and production runs while meeting quality, efficiency, and scheduling targets.
• Support the manufacture of fluorescently labeled antibody conjugates used in life science research applications.
• Perform protein concentration and quality assessments using UV-Vis spectrophotometry and other analytical methods.
• Prepare buffers, reagents, and solutions required for purification and conjugation workflows.
• Complete detailed batch records, production documentation, and laboratory records in accordance with company procedures.
• Troubleshoot routine process, equipment, and analytical issues to ensure uninterrupted production.
• Apply laboratory calculations related to concentrations, dilutions, yields, and process performance.
• Collaborate with Manufacturing, Quality, R&D, and Operations teams to achieve production goals.
• After training, independently manage second-shift purification activities and drive continuous process improvement.

Required Qualifications

• Bachelor's degree in Biology, Biochemistry, Biotechnology, Cell Biology, Molecular Biology, or a related Life Science discipline.
• Minimum 2 years of relevant laboratory experience in biotechnology, biopharmaceutical, or research environments.
• Hands-on experience with antibody purification, protein purification, or chromatography-based workflows.
• Experience operating FPLC and/or ÄKTA chromatography systems.
• Knowledge of spectrophotometry and protein quantification methods.
• Strong laboratory math skills, including dilution, concentration, and yield calculations.
• Excellent documentation, organizational, and recordkeeping practices.
• Strong troubleshooting and problem-solving abilities.
• Ability to work independently in a fast-paced production environment after training.
• Ability to occasionally lift up to 50 pounds.

Preferred Qualifications

• Experience working in a GMP, ISO-regulated, or biotechnology manufacturing environment.
• Knowledge of monoclonal antibody development, purification, and conjugation processes.
• Familiarity with protein characterization techniques and analytical testing methods.
• Experience supporting manufacturing schedules and production-driven operations.
• Demonstrated commitment to quality, compliance, and continuous improvement initiatives.

Work Environment This position is based onsite in our Carlsbad laboratory and manufacturing facility. Team members work with chromatography systems, spectrophotometers, and other standard biotechnology laboratory equipment in a fast-paced production environment. Appropriate safety controls are in place for handling laboratory chemicals and other materials. Following training, the Scientist II will independently manage assigned second-shift production activities while maintaining quality, accuracy, and efficiency. Why Join the Team?

• Contribute to products that support cutting-edge cell signaling and life science research.
• Gain hands-on experience with advanced antibody purification and bioconjugation technologies.
• Expand your expertise in protein science, chromatography, and biotechnology manufacturing.
• Work in a collaborative, science-driven environment with opportunities for technical growth and advancement.
• Play a critical role in delivering high-quality reagents that enable scientific discovery worldwide.

If you're passionate about protein science, antibody purification, and biotechnology manufacturing, we'd love to hear from you. Apply today and help advance the next generation of scientific research. Job Type & LocationThis is a Contract to Hire position based out of Carlsbad, CA. Pay and BenefitsThe pay range for this position is $33.00 - $37.00/hr. Individual compensation offered for this position within this range will depend on many factors, including qualifications, skills, relevant experience, job knowledge, geographic location, internal equity, and other pertinent job-related factors.Eligibility requirements apply to some benefits and may depend on your job classification and length of employment. Benefits are subject to change and may be subject to specific elections, plan, or program terms. If eligible, the benefits

available for this temporary role may include the following:

Medical, dental & vision Critical Illness, Accident, and Hospital 401(k) Retirement Plan Pre-tax and Roth post-tax contributions available Life Insurance (Voluntary Life & AD&D for the employee and dependents) Short and long-term disability Health Spending Account (HSA) Transportation benefits Employee Assistance Program Time Off/Leave (PTO, Vacation or Sick Leave) Job Type & LocationThis is a Contract to Hire position based out of Carlsbad, CA. Application DeadlineThis position is anticipated to close on Nov 13, 2026. Workplace TypeThis is a fully onsite position in Carlsbad,CA.About Actalent

Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 20,000 consultants and 5,000 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500. We are proud to be an Engineering News-Record (ENR) Top 500 Design Firm for our engineering design services and a ClearlyRated Best of Staffing® winner for both client and talent service.

The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.

If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing process due to a disability, please email actalentaccommodation@actalentservices.com for other accommodation options.

San Francisco Fair Chance Ordinance:

Pursuant to the San Francisco Fair Chance Ordinance, for all positions located in the city and county of San Francisco, we will consider for employment qualified applicants with arrest and conviction records.

Massachusetts Lie Detector:

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Use of Artificial Intelligence (AI):

We may use Artificial Intelligence (AI) to support parts of our hiring process, including sourcing, screening, and evaluating candidates. AI helps assess applications and qualifications, but final decisions are made by our hiring team. By applying, you acknowledge and agree that your application may be reviewed using AI tools.