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Added 1 hour ago
TAds Sr Engineer, Software
T-Mobile
NEW YORK, NY
…engineers to develop software components using technologies such as virtualization, microservices, software-defined networking, network functions virtualization, and big data. It requires…
Added 1 hour ago
ES
Lead GIS Solution Engineer - Defense
Environmental Systems Research Institute Inc.
Louisville, CO
- $120,016 to $201,344 USD / year
Esri is seeking a lead GIS Solution Engineer to serve as a technical leader and trusted advisor to Defense and Intelligence organizations. You will bring deep ArcGIS expertise, mission…
Added 3 hours ago
IT Cloud Engineer, Engineering Platform Automation
Mayo Clinic
Rochester, MN
The IT Cloud Engineer – Engineering Platform Automation is responsible for designing, developing, operating, and continuously evolving Mayo Clinic's Engineering Front Door - a cloud-native…
Added 5 hours ago
Networks Systems Engineer III
Auria (Boecore LLC)
Colorado Springs, CO
Auria is looking to hire a Networks Systems Engineer III to support the Command, Control, Battle Management, and Communications(C2BMC) program. This role is onsite in Colorado Springs, CO.…
Added 5 hours ago
2027 Cloud Solutions Engineer / Site Reliability Grad Intern
The Aerospace Corpor
Colorado Springs, CO
…place in space. Aerospace Corporation is hiring Cloud Solutions Engineer / Site Reliability Grad level Interns for the Cloud Platforms and Architectures Department in the Information…
Added 5 hours ago
MS
Field Engineer - Emergency Call Handling
Motorola Solutions, Inc.
Denver, CO
- $75,000 to $85,000 USD / year
The Emergency Call Handling (ECH) Field Engineer will report to the ECH Field Engineer Manager. The Field Engineer is ultimately accountable for the system being implemented based on the…
Added 7 hours ago
Senior Systems Engineer (IT Infrastructure)
Avint
Tysons, VA
Avint is seeking a highly skilled Senior Systems Engineer to support a mission-critical program within the National Capital Region. This role focuses on the design, implementation,…
Added 8 hours ago
Principal Automation Engineer Optical Inspection SME
J&J Family of Companies
Wilson, NC
Senior Automation Engineer will lead internal team members, suppliers, OEMs, system integrators, Digital/IT partners, automation-system owners, and cross-functional stakeholders to deliver…
Added 8 hours ago
Integration Engineer
Avalore, LLC
Arlington, VA
The Integration Engineer will perform the software integration activities required for the WDP System. This person will focus on ensuring that all disparate software components - including…
Added 8 hours ago
Cloud Design Engineer, Level 2
Avalore, LLC
Annapolis Junction, MD
Avalore is seeking a Cloud Design Engineer, Level 2. The Cloud Design Engineer develops, maintains, and enhances complex and diverse Web-Based User Interfaces that interact with BigData…
Added 8 hours ago
Cloud Software Engineer, Level 2
Avalore, LLC
Annapolis Junction, MD
Avalore is seeking a Cloud Software Engineer. The Cloud Software Engineer develops, maintains, and enhances complex and diverse Big-Data Cloud systems based upon documented requirements.…
Added 8 hours ago
Cloud Software Engineer, Level 3
Avalore, LLC
Annapolis Junction, MD
Avalore is seeking a Cloud Design Engineer, Level 3. The Cloud Software Engineer develops, maintains, and enhances complex and diverse Big-Data Cloud systems based upon documented…
Added 8 hours ago
M
Senior Principal Verification Engineer
Microsoft
NC · TX · Raleigh, NC · Austin, TX · Raleigh · Austin
- $165,600 to $331,200 USD / year
We are looking for a Senior Principal Verification Engineer to join the team to support our mission and culture.
Added 9 hours ago
Senior Container Platform Engineer
Charles Schwab
Austin, TX
We are seeking a Senior Container Platform Engineer to join our Infrastructure Platforms organization, helping build and operate resilient, secure, and repeatable enterprise container…
Added 10 hours ago
AC
Senior / Staff / Principal Platform Engineer
AppGate Cybersecurity, Inc.
Remote, United States
- $180,000 to $270,000 USD / year
We’re looking for a Senior, Staff or Principal Platform Engineer with deep expertise in Python, Linux systems and production platform engineering.
Added 10 hours ago
AC
Senior Sales Engineer
AppGate Cybersecurity, Inc.
Remote, United States
- $175,000 to $225,000 USD / year
The Senior Sales Engineer (SE) is the senior pre-sales subject matter expert for AppGate ZTNA and owns the technical engagement with commercial prospects from first meeting through…
Added 10 hours ago
AC
Senior Sales Engineer
AppGate Cybersecurity, Inc.
Remote, United States
- $175,000 to $225,000 USD / year
The Senior Sales Engineer (SE) is the senior pre-sales subject matter expert for AppGate ZTNA and owns the technical engagement with commercial prospects from first meeting through…
Added 10 hours ago
AC
Senior Sales Engineer
AppGate Cybersecurity, Inc.
Remote, United States
- $175,000 to $225,000 USD / year
The Senior Sales Engineer (SE) is the senior pre-sales subject matter expert for AppGate ZTNA and owns the technical engagement with commercial prospects from first meeting through…
Added 10 hours ago
AC
Network Engineer - Tier 3
AppGate Cybersecurity, Inc.
Remote, United States
- $110,000 to $120,000 USD / year
We are looking for a remote network engineer to provide enterprise-level support for our Zero Trust Network Access (ZTNA) solution. Due to the level of integration our Zero Trust platform…
Added 10 hours ago
AC
Network Engineer - Tier 3
AppGate Cybersecurity, Inc.
Remote, United States
- $110,000 to $120,000 USD / year
We are looking for a remote network engineer to provide enterprise-level support for our Zero Trust Network Access (ZTNA) solution. Due to the level of integration our Zero Trust platform…
Added 10 hours ago
AC
Network Engineer - Tier 3
AppGate Cybersecurity, Inc.
Remote, United States
- $110,000 to $120,000 USD / year
We are looking for a remote network engineer to provide enterprise-level support for our Zero Trust Network Access (ZTNA) solution. Due to the level of integration our Zero Trust platform…
Added 10 hours ago
Sr. Solutions Architect/Sales Engineer-AI Infrastructure (GPU) -West Coast
Liqid
Remote, United States
The right person can whiteboard a GPU inference cluster with a customer’s principal engineer, run a disciplined PoC against agreed success criteria, and translate the technical outcome into…
Added 10 hours ago
Sr. Solutions Architect/Sales Engineer-AI Infrastructure (GPU) -West Coast
Liqid
Remote, United States
The right person can whiteboard a GPU inference cluster with a customer’s principal engineer, run a disciplined PoC against agreed success criteria, and translate the technical outcome into…
Added 10 hours ago
Systems Engineer 3
DCCA
Annapolis Junction, MD
We are seeking a System Engineer who has experience working all phases of the system engineering lifecycle from concept to sustainment. This includes the ability to produce documentation…
Added 15 hours ago
Linux Systems Administrator
SAIC
Chantilly, VA
…enjoys solving challenging technical problems across Linux, virtualization, and infrastructure…

10x Genomics

Senior IT Systems Engineer

Pleasanton, CA, United States

$136,500 to $184,700 USD / year

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Job details

Pay: $136,500 to $184,700 USD / year
Posting language: English
Posted: Nov 3, 2026

Original job description

About 10x Genomics

At 10x Genomics, accelerating our understanding of biology is more than a mission for us. It is a commitment. This is the century of biology, and the breakthroughs we make now have the potential to change the world.

We enable scientists to advance their research, allowing them to address scientific questions they did not even know they could ask. Our tools have enabled fundamental discoveries across biology including cancer, immunology, and neuroscience.

About The Role

Information technology is a vital and integral part of our success. At 10x Genomics, IT not only provides a secure, stable, and scalable infrastructure for R&D, manufacturing, and business operations, it serves as a catalyst for innovation and productivity. We are looking for an exceptional Senior Systems Engineer with strong knowledge of Windows and virtualization platforms and extensive experience in building and maintaining mission-critical IT infrastructure to join our IT team. If you are a self-starter who is passionate about building and operating scalable and reliable IT infrastructure and is excited to work in a highly collaborative environment alongside a diverse team of experts every day, join us at 10x Genomics.

What you will be doing

Design, build, maintain and monitor our mission-critical Windows enterprise infrastructure systems and services across global footprint.
Manage our Global Active Directory & Microsoft Entra ID (formerly Azure AD) environment.
Maintain a secure and stable IT environment; Deploying patch management software, policy enforcement, systems hardening and systems / software upgrades.
Manage enterprise backup and disaster recovery solutions.
Create and maintain detailed documentation of system design, implementation and configuration.
Participate in a shared operational on-call rotation to support our production environment.
Lead post-incident reviews to identify root causes and implement long-term preventative fixes.

Minimum Qualifications

5 years IT experience with managing Windows Infrastructure and core services such as Active Directory, Microsoft Entra ID, Endpoint management, DNS and DHCP in a production environment.
Extensive experience with virtualization technologies and hypervisors, such as VMware ESXi/vCenter and Proxmox VE.
Experience with system architecture and building production environments on AWS.
Experience with enterprise backup, disaster recovery, alerting and monitoring solutions.
Strong understanding of encryption, data security and patch management best practices.
Experience scripting in Powershell, Bash or Python.
Experience with IaC and configuration management tools (Ansible, Terraform) to automate system provisioning.

Preferred Skills & Experience

Working knowledge of Linux such as regular day-to-day sysadmin responsibilities (build systems, management, permissions, network mounts).
Familiar with Identity Access & Management tools (Okta, SAML2.0 / OIDC protocols).
Familiar with Microsoft Intune for unified endpoint management and policy enforcement.
Strong analytical and organizational skills.
Excellent oral and written communication skills.

Below is the base pay range for this full-time position. The actual base pay will depend on several factors unique to each candidate, including one’s skills, qualifications, and experience. At 10x, base pay is also just one component of the Company’s total compensation package. This role is also eligible for 10x’s equity grants, its comprehensive health and retirement benefit programs, and its annual bonus program or sales incentive program. During the hiring process, your 10x recruiter can share more about the Company’s total compensation package.

USD 136,500-184,700 / year

Our teams are empowered and encouraged to follow their passions, pursue new ideas, and perform at their best in an inclusive and dynamic environment. We know that behind every scientific breakthrough, there is a deep infrastructure of talented people driving the life sciences industry and making it possible for scientists and clinicians to make new strides. We are dedicated to finding the very best person for every aspect of our work because the innovations and discoveries that we enable together will lead to better technologies, better treatments, and a better future. Find out how you can make a 10x difference.

Individuals seeking employment at 10x Genomics are considered without regards to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation, or any other characteristic protected by applicable law.

10x does not accept unsolicited applicants submitted by third-party recruiters or agencies. Any resume or application submitted to 10x without a vendor agreement in place will be considered unsolicited and property of 10x, and 10x will not pay a placement fee.

Please be aware of recruitment scams impersonating 10x Genomics. All recruiting communication will come from email addresses @10xgenomics.com. We also want to encourage you to apply to 10x Genomics positions directly on our careers site, https://careers.kula.ai/10xgenomics?pid=171812447059&domain=10xgenomics.com or from reputable third party sites, such as LinkedIn or Indeed. We will never request payment or sensitive personal information during the recruiting process.

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